Romans 14 gives us some wisdom on this:

2 For one believeth that he may eat all things: another, who is weak, eateth herbs.
3 Let not him that eateth despise him that eateth not; and let not him which eateth not judge him that eateth: for God hath received him.

Paul applies his teaching to drinking wine later in the chapter. Those who are opposed to drinking wine should take this advise as well. The should not judge those who drink in moderation, and give thanks to God.

I don’t know if there were any teetotalers in Paul’s day who’d invented a doctrine of it. Timothy may have been completely abstaining for whatever reason, and Paul did not agree with that. Paul could have been a temporary teetotaler if he had a Nazarite vow, but from grapes, grape juice, and raisins also. I don’t think the post-Wesley doctrine existed then. There may have been some gnostic type groups or ascetics of different types who wanted to abstain from certain foods to be holy.

My guess would be Paul’s reference to drinking wine might have had something to do with the fear that some of the wine sold in the marketplace had been poured out as a libation to a false god before being sold. Either that or it could have been some sort of kosher issue.